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A major introduction to GC376!

GC376 is in stock now! GC376 (cas# 1416992-39-6) is a representative compound of the dipeptidyl transition state 3CLpro inhibitors, inhibits the replication of viruses TGEV, FIPV and PTV with IC50 values of 0.15, 0.2 and 0.15 μM.

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GW590735 CAS No. : 622402-22-6 is in stock now!

GW590735 is a potent and selective agonist of PPARα with an EC50 value of 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivity versus PPARγ and PPARδ. GW590735 significantly increased HDL cholesterol, decreased LDL and VLDL cholesterol, and significantly reduced triglycerides. Maximal increases in HDL cholesterol were 37%, 53%, and 84% with fenofibrate, torcetrapib, and GW590735, respectively.

Custom Synthesis

MuseChem engages in total-support business for research and development of organic compounds for the chemical, pharmaceutical and agrochemical industries. We provide custom manufacturing and process research services on scales ranging from milligrams to kilograms. MuseChem’s scientists in the chemistry team are well trained, can handle even the most complex chemical synthesis and characterization projects, completing the project on your required timeframe. Your inquiry will b e evaluated within a few days to provide you with a quote complemented by a synthetic scheme. The quote is calculated on the basis of the current FTE rate. We deliver detailed biweekly reports with expected delivery dates. Each project is treated under the confidentiality agreement. We won't charge our clients for failed syntheses. We offer high-quality and cost-effective custom synthesis service under strict confidentiality including the following: ● Small-Scale and large scale manufacturing ● Process dev...

LGD-4033

LGD-4033 is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity. in vitro : LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, binds androgen receptor with high affinity and selectivity. in vivo : LGD-4033 has demonstrated anabolic activity in the muscle, anti-resorptive and anabolic activity in bone, and robust selectivity for muscle versus prostate In animal models. LGD-4033 is well tolerated, has a long elimination half-life and dose-proportional accumulation upon multiple dosing. LGD-4033 is safe, has favorable pharmacokinetic profile, and increases lean body mass even during this short period without change in prostate-specific antigen. http://www.musechem.com/product/I000595/LGD-4033.html